Drug related morbidity and mortality updating the cost of illness Chennaifreesex
Keywords: drug related problems, drug therapy problems, high alert medication, Jordan, pharmaceutical care, treatment related problems Introduction Treatment-related problems (TRPs) are associated with the use of medications that result in decreased therapeutic outcomes, which are usually addressed by pharmacists. TRPs can lead to decreased disease control and adverse effects.
Such TRPs might lead to overutilization of health care resources, with associated high costs for the health care system, in particular for elderly patients.
Examples of these medications are antiretroviral agents, chemotherapeutic agents, hypoglycemic agents and insulin, immunosuppressants, opioids, carbamazepine, midazolam (liquid), propylthiouracil, warfarin, and pregnancy category X drugs.
Hypertension, diabetes mellitus, and dyslipidemia were the most common diseases associated with different subtypes of TRPs.The medication groups most commonly associated with TRPs were cardiovascular (53.0%), endocrine (18.1%), and gastrointestinal (7.7%) drugs.The most common specific drugs associated with TRPs from any category were atorvastatin (12.5%), metformin (8.5%), simvastatin (6.2%), and enalapril (5.9%).A convenient and easy trigger tools would be to formulate a list of drugs commonly associated with TRPs as a targeting mechanism.This concept has been adopted by accreditation bodies such as the Joint Commission (Oakbrook Terrace, IL, USA), which maintains a list of high-alert medications.